Analgesic tolerance to morphine is regulated by PPARγ

BACKGROUND AND PURPOSE: Opioid drugs are potent analgesics. However, their chronic use leads to the rapid development of tolerance to their analgesic effects and subsequent increase of significant side effects, including drug dependence and addiction. Here, we investigated the role of PPARγ in the d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Br J Pharmacol
मुख्य लेखकों: de Guglielmo, Giordano, Kallupi, Marsida, Scuppa, Giulia, Stopponi, Serena, Demopulos, Gregory, Gaitanaris, George, Ciccocioppo, Roberto
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BlackWell Publishing Ltd 2014
विषय:
Research Papers
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294048/
https://ncbi.nlm.nih.gov/pubmed/25048682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12851
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