PPARγ Activation Attenuates Opioid Consumption and Modulates Mesolimbic Dopamine Transmission

PPARγ is one of the three isoforms identified for the peroxisome proliferator-activated receptors (PPARs) and is the receptor for the thiazolidinedione class of anti-diabetic medications including pioglitazone. PPARγ has been long studied for its role in adipogenesis and glucose metabolism, but the...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: de Guglielmo, Giordano, Melis, Miriam, De Luca, Maria Antonietta, Kallupi, Marsida, Li, Hong Wu, Niswender, Kevin, Giordano, Antonio, Senzacqua, Martina, Somaini, Lorenzo, Cippitelli, Andrea, Gaitanaris, George, Demopulos, Gregory, Damadzic, Ruslan, Tapocik, Jenica, Heilig, Markus, Ciccocioppo, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330506/
https://ncbi.nlm.nih.gov/pubmed/25311134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.268
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