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Antiproliferation Activity of a Small Molecule Repressor of Liver Receptor Homolog 1

The orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) is a potent regulator of cholesterol metabolism and bile acid homeostasis. Recently, LRH-1 has been shown to play an important role in intestinal inflammation and in the progression of estrogen receptor positive and negative breast...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Corzo, Cesar A., Mari, Yelenis, Chang, Mi Ra, Khan, Tanya, Kuruvilla, Dana, Nuhant, Philippe, Kumar, Naresh, West, Graham M., Duckett, Derek R., Roush, William R., Griffin, Patrick R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293447/
https://ncbi.nlm.nih.gov/pubmed/25473120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.095554
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