Cardiac thromboxane A2 receptor activation does not directly induce cardiomyocyte hypertrophy but does cause cell death that is prevented with gentamicin and 2-APB

BACKGROUND: We have previously shown that the thromboxane (TXA2) receptor agonist, U46619, can directly induce ventricular arrhythmias that were associated with increases in intracellular calcium in cardiomyocytes. Since TXA2 is an inflammatory mediator and induces direct calcium changes in cardiomy...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:BMC Pharmacol Toxicol
Main Authors: Touchberry, Chad D, Silswal, Neerupma, Tchikrizov, Vladimir, Elmore, Christopher J, Srinivas, Shubra, Akthar, Adil S, Swan, Hannah K, Wetmore, Lori A, Wacker, Michael J
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293009/
https://ncbi.nlm.nih.gov/pubmed/25519194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-15-73
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla