Skeletal Muscle, but not Cardiovascular Function, Is Altered in a Mouse Model of Autosomal Recessive Hypophosphatemic Rickets

Autosomal recessive hypophosphatemic rickets (ARHR) is a heritable disorder characterized by hypophosphatemia, osteomalacia, and poor bone development. ARHR results from inactivating mutations in the DMP1 gene with the human phenotype being recapitulated in the Dmp1 null mouse model which displays e...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Wacker, Michael J., Touchberry, Chad D., Silswal, Neerupma, Brotto, Leticia, Elmore, Chris J., Bonewald, Lynda F., Andresen, Jon, Brotto, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866514/
https://ncbi.nlm.nih.gov/pubmed/27242547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00173
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