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Skeletal Muscle, but not Cardiovascular Function, Is Altered in a Mouse Model of Autosomal Recessive Hypophosphatemic Rickets

Autosomal recessive hypophosphatemic rickets (ARHR) is a heritable disorder characterized by hypophosphatemia, osteomalacia, and poor bone development. ARHR results from inactivating mutations in the DMP1 gene with the human phenotype being recapitulated in the Dmp1 null mouse model which displays e...

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Библиографические подробности
Опубликовано в: :Front Physiol
Главные авторы: Wacker, Michael J., Touchberry, Chad D., Silswal, Neerupma, Brotto, Leticia, Elmore, Chris J., Bonewald, Lynda F., Andresen, Jon, Brotto, Marco
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866514/
https://ncbi.nlm.nih.gov/pubmed/27242547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00173
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