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A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies

The purposes of the present study were to further evaluate the biologic significance of the CD22ΔE12 molecular lesion and determine if it could serve as a molecular target for RNA interference (RNAi) therapy. We show that both pediatric and adult B-lineage lymphoid malignancies are characterized by...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Uckun, Fatih M., Qazi, Sanjive, Ma, Hong, Yin, Lichen, Cheng, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292938/
https://ncbi.nlm.nih.gov/pubmed/25599086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2014.10.013
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