Structural and mechanistic insight into Holliday junction dissolution by Topoisomerase IIIα and RMI1

Repair of DNA double-strand breaks via homologous recombination can produce double Holliday junctions (dHJs) that require enzymatic separation. Topoisomerase IIIα (TopIIIα) together with RMI1 disentangles the final hemicatene intermediate obtained once dHJs have converged. How binding of RMI1 to Top...

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Detaylı Bibliyografya
Yayımlandı:Nat Struct Mol Biol
Asıl Yazarlar: Bocquet, Nicolas, Bizard, Anna H., Abdulrahman, Wassim, Larsen, Nicolai B., Faty, Mahamadou, Cavadini, Simone, Bunker, Richard D., Kowalczykowski, Stephen C., Cejka, Petr, Hickson, Ian D., Thomä, Nicolas H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292918/
https://ncbi.nlm.nih.gov/pubmed/24509834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2775
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