Top3-Rmi1 dissolve Rad51-mediated D-loops by a topoisomerase-based mechanism

The displacement loop (D-loop) is the DNA strand invasion product formed during homologous recombination. Disruption of nascent D-loops represents a mechanism of anti-recombination. During Synthesis-Dependent Strand Annealing D-loop disruption after extension of the invading strand is an integral st...

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Udgivet i:Mol Cell
Main Authors: Fasching, Clare L., Cejka, Petr, Kowalczykowski, Stephen C., Heyer, Wolf-Dietrich
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338411/
https://ncbi.nlm.nih.gov/pubmed/25699708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.01.022
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