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Decatenation of DNA by the S. cerevisiae Sgs1–Top3–Rmi1 and RPA complex: A mechanism for disentangling chromosomes

Genetic evidence indicates that Saccharomyces cerevisiae Sgs1, Top3, and Rmi1 resolve topologically linked intermediates arising from DNA replication and recombination. Using purified proteins, we show that Sgs1, Top3, Rmi1, and replication protein-A (RPA) coordinate catenation and decatenation of d...

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Détails bibliographiques
Auteurs principaux: Cejka, Petr, Plank, Jody L., Dombrowski, Christopher C., Kowalczykowski, Stephen C.
Format: Artigo
Langue:Inglês
Publié: 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462259/
https://ncbi.nlm.nih.gov/pubmed/22885009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.06.032
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