Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction

INTRODUCTION: Activation of the inflammasome has been implicated in the pathology of various autoinflammatory and autoimmune diseases. While the NLRP3 inflammasome has been linked to arthritis progression, little is known about its synovial regulation or contribution to joint histopathology. Regulat...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Greenhill, Claire J, Jones, Gareth W, Nowell, Mari A, Newton, Zarabeth, Harvey, Ann K, Moideen, Abdul N, Collins, Fraser L, Bloom, Anja C, Coll, Rebecca C, Robertson, Avril AB, Cooper, Matthew A, Rosas, Marcela, Taylor, Philip R, O’Neill, Luke A, Humphreys, Ian R, Williams, Anwen S, Jones, Simon A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292830/
https://ncbi.nlm.nih.gov/pubmed/25175678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0419-y
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