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Regulation of Early Cartilage Destruction in Inflammatory Arthritis by Death Receptor 3

OBJECTIVE: To investigate the role of death receptor 3 (DR-3) and its ligand tumor necrosis factor–like molecule 1A (TL1A) in the early stages of inflammatory arthritis. METHODS: Antigen-induced arthritis (AIA) was generated in C57BL/6 mice deficient in the DR-3 gene (DR3(−/−)) and their DR3(+/+) (w...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Wang, Eddie C Y, Newton, Zarabeth, Hayward, Olivia A, Clark, Stephen R, Collins, Fraser, Perks, William V, Singh, Ravinder K, Twohig, Jason P, Williams, Anwen S
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286106/
https://ncbi.nlm.nih.gov/pubmed/25044706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38770
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