Leveraging chemotherapy-induced lymphopenia to potentiate cancer immunotherapy

First-line chemotherapy to combat primary malignant brain cancer is often accompanied by lymphopenic immunologic deficiency. Although counterintuitive, chemotherapy-induced lymphopenia can provide excellent host conditioning that may actually be leveraged to potentiate antitumor immunotherapy. We di...

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Publicado en:Oncoimmunology
Autores principales: Sanchez-Perez, Luis, Suryadevara, Carter M, Choi, Bryan D, Reap, Elizabeth A, Sampson, John H
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292586/
https://ncbi.nlm.nih.gov/pubmed/25610727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.944054
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