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Immunotherapy gone viral: Bortezomib and oHSV enhance antitumor NK cell activity

Oncolytic viruses (OV), proteasome inhibitors, and NK cell immunotherapy have all been studied extensively as monotherapies but have never been evaluated in combination. Synergetic treatment of OV-infected glioblastomas (GBM) with a proteasome inhibitor induces necroptotic cell death to enhance NK c...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Suryadevara, Carter M., Riccione, Katherine, Sampson, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093093/
https://ncbi.nlm.nih.gov/pubmed/27521450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1666
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