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Immunotherapy gone viral: Bortezomib and oHSV enhance antitumor NK cell activity
Oncolytic viruses (OV), proteasome inhibitors, and NK cell immunotherapy have all been studied extensively as monotherapies but have never been evaluated in combination. Synergetic treatment of OV-infected glioblastomas (GBM) with a proteasome inhibitor induces necroptotic cell death to enhance NK c...
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| Veröffentlicht in: | Clin Cancer Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5093093/ https://ncbi.nlm.nih.gov/pubmed/27521450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1666 |
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