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Immune-mediated tumor evolution: Nanog links the emergence of a stem like cancer cell state and immune evasion

Tumor cells undergo molecular evolution under immune pressure. Using a murine metastatic lung cancer model, we recently reported that evolutionary pressure enforced through vaccination incites gain of Nanog, a master transcription factor that mediates both emergence of a stem-like cancer cell state...

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Bibliografiska uppgifter
I publikationen:Oncoimmunology
Huvudupphovsmän: Mao, Chih-Ping, Wu, Tc, Song, Kwon-Ho, Kim, Tae Woo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292413/
https://ncbi.nlm.nih.gov/pubmed/25610734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.947871
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