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Immune-mediated tumor evolution: Nanog links the emergence of a stem like cancer cell state and immune evasion
Tumor cells undergo molecular evolution under immune pressure. Using a murine metastatic lung cancer model, we recently reported that evolutionary pressure enforced through vaccination incites gain of Nanog, a master transcription factor that mediates both emergence of a stem-like cancer cell state...
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| Udgivet i: | Oncoimmunology |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292413/ https://ncbi.nlm.nih.gov/pubmed/25610734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.947871 |
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