Immune-mediated tumor evolution: Nanog links the emergence of a stem like cancer cell state and immune evasion

Tumor cells undergo molecular evolution under immune pressure. Using a murine metastatic lung cancer model, we recently reported that evolutionary pressure enforced through vaccination incites gain of Nanog, a master transcription factor that mediates both emergence of a stem-like cancer cell state...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncoimmunology
Prif Awduron: Mao, Chih-Ping, Wu, Tc, Song, Kwon-Ho, Kim, Tae Woo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2014
Pynciau:
Author's View
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292413/
https://ncbi.nlm.nih.gov/pubmed/25610734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.947871
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