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Structure-Activity of Sulfones and Sulfonamides on Dihydropteroate Synthetase from Neisseria meningitidis

The molecular interaction of various sulfones and sulfonamides with partially purified dihydropteroate synthetase from Neisseria meningitidis M-166 has been examined. The mode of action of the sulfones was similar to that of the sulfonamides. Both groups of drugs were competitive inhibitors of dihyd...

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Bibliografski detalji
Glavni autori: Ho, Richard I., Corman, Leonard, Morse, Stephen A., Schneider, Herman
Format: Artigo
Jezik:Inglês
Izdano: 1975
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC429223/
https://ncbi.nlm.nih.gov/pubmed/808157
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