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Structure-Activity of Sulfones and Sulfonamides on Dihydropteroate Synthetase from Neisseria meningitidis

The molecular interaction of various sulfones and sulfonamides with partially purified dihydropteroate synthetase from Neisseria meningitidis M-166 has been examined. The mode of action of the sulfones was similar to that of the sulfonamides. Both groups of drugs were competitive inhibitors of dihyd...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Ho, Richard I., Corman, Leonard, Morse, Stephen A., Schneider, Herman
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1975
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429223/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/808157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.7.6.758
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