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Mechanism of the Reduction of the Native Intermediate in the Multicopper Oxidases: Insights into Rapid Intramolecular Electron Transfer in Turnover

[Image: see text] The multicopper oxidases (MCOs) are the family of enzymes that catalyze the 4-electron reduction of O(2) to H(2)O coupled to the four 1-electron oxidations of substrate. In the catalytic cycle electrons are transferred intramolecularly over ∼13 Å from a Type 1 (T1) Cu site that acc...

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Heppner, David E., Kjaergaard, Christian H., Solomon, Edward I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291763/
https://ncbi.nlm.nih.gov/pubmed/25490729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja509150j
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