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Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling
The MAP kinase TGFβ-activated kinase (TAK1) plays a crucial role in physiologic and pathologic cellular functions including cell survival, differentiation, apoptosis, inflammation, and oncogenesis. However, the entire repertoire of its mechanism of action has not been elucidated. Here, we found that...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291677/ https://ncbi.nlm.nih.gov/pubmed/25535389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415213112 |
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