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Constitutive Activation of IKK2/NF-κB Impairs Osteogenesis and Skeletal Development
Pathologic conditions impair bone homeostasis. The transcription factor NF-κB regulates bone homeostasis and is central to bone pathologies. Whereas contribution of NF-κB to heightened osteoclast activity is well-documented, the mechanisms underlying NF-κB impact on chondrocytes and osteoblasts are...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949987/ https://ncbi.nlm.nih.gov/pubmed/24618907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091421 |
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