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Constitutively Active Canonical NF-κB Pathway Induces Severe Bone Loss in Mice
Physiologic osteoclastogenesis entails activation of multiple signal transduction pathways distal to the cell membrane receptor RANK. However, atypical osteoclastogenesis driven by pro-inflammatory stimuli has been described. We have reported recently a novel mechanism whereby endogenous mutational...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369901/ https://ncbi.nlm.nih.gov/pubmed/22685599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038694 |
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