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Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling

The MAP kinase TGFβ-activated kinase (TAK1) plays a crucial role in physiologic and pathologic cellular functions including cell survival, differentiation, apoptosis, inflammation, and oncogenesis. However, the entire repertoire of its mechanism of action has not been elucidated. Here, we found that...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Swarnkar, Gaurav, Karuppaiah, Kannan, Mbalaviele, Gabriel, Chen, Tim (Hung-Po), Abu-Amer, Yousef
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291677/
https://ncbi.nlm.nih.gov/pubmed/25535389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415213112
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