A Soluble Adenylyl Cyclase Form Targets to Axonemes and Rescues Beat Regulation in Soluble Adenylyl Cyclase Knockout Mice

Ciliary beating is important for effective mucociliary clearance. Soluble adenylyl cyclase (sAC) regulates ciliary beating, and a roughly 50-kD sAC variant is expressed in axonemes. Normal human bronchial epithelial (NHBE) cells express multiple sAC splice variants: full-length sAC; variants with ca...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Cell Mol Biol
Prif Awduron: Chen, Xi, Baumlin, Nathalie, Buck, Jochen, Levin, Lonny R., Fregien, Nevis, Salathe, Matthias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291545/
https://ncbi.nlm.nih.gov/pubmed/24874272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0542OC
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