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Differential retrotranslocation of mitochondrial Bax and Bak
The Bcl-2 proteins Bax and Bak can permeabilize the outer mitochondrial membrane and commit cells to apoptosis. Pro-survival Bcl-2 proteins control Bax by constant retrotranslocation into the cytosol of healthy cells. The stabilization of cytosolic Bax raises the question whether the functionally re...
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| Udgivet i: | EMBO J |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291481/ https://ncbi.nlm.nih.gov/pubmed/25378477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488806 |
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