The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation

The pro-apoptotic Bcl-2 protein Bax can permeabilize the outer mitochondrial membrane and therefore commit human cells to apoptosis. Bax is regulated by constant translocation to the mitochondria and retrotranslocation back into the cytosol. Bax retrotranslocation depends on pro-survival Bcl-2 prote...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Lauterwasser, Joachim, Todt, Franziska, Zerbes, Ralf M., Nguyen, Thanh Ngoc, Craigen, William, Lazarou, Michael, van der Laan, Martin, Edlich, Frank
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020405/
https://ncbi.nlm.nih.gov/pubmed/27620692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32994
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