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Mechanism of β-Lactam Action in Streptococcus pneumoniae: the Piperacillin Paradox
The human pathogen Streptococcus pneumoniae has been treated for decades with β-lactam antibiotics. Its resistance is now widespread, mediated by the expression of mosaic variants of the target enzymes, the penicillin-binding proteins (PBPs). Understanding the mode of action of β-lactams, not only i...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291406/ https://ncbi.nlm.nih.gov/pubmed/25385114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04283-14 |
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