Impact of Nonlinear Interactions of Pharmacokinetics and MICs on Sputum Bacillary Kill Rates as a Marker of Sterilizing Effect in Tuberculosis

The relationships between antituberculosis drug exposure and treatment effects on humans receiving multidrug therapy are complex and nonlinear. In patients on treatment, an analysis of the rate of decline in the sputum bacillary burden reveals two slopes. The first is the α-slope, which is thought t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Chigutsa, Emmanuel, Pasipanodya, Jotam G., Visser, Marianne E., van Helden, Paul D., Smith, Peter J., Sirgel, Frederick A., Gumbo, Tawanda, McIlleron, Helen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Clinical Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291375/
https://ncbi.nlm.nih.gov/pubmed/25313213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03931-14
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak