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In Vitro and Intracellular Activities of Peptide Deformylase Inhibitor GSK1322322 against Legionella pneumophila Isolates

GSK1322322, a novel peptide deformylase inhibitor currently in development as an oral and intravenous agent for the treatment of hospitalized community-acquired bacterial pneumonia, showed poor in vitro activity against a panel of 50 Legionella pneumophila strains, with MICs ranging from 1 to 16 μg/...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Dubois, Jacques, Dubois, Maïtée, Martel, Jean-François, Aubart, Kelly, Butler, Deborah
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291349/
https://ncbi.nlm.nih.gov/pubmed/25348534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04006-14
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