Neuroprotective effects of the anti‐cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders

BACKGROUND AND PURPOSE: Anti-retrovirals have improved and extended the life expectancy of patients with HIV. However, as this population ages, the prevalence of cognitive changes is increasing. Aberrant activation of kinases, such as receptor tyrosine kinases (RTKs) and cyclin-dependent kinase 5 (C...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Wrasidlo, Wolf, Crews, Leslie A, Tsigelny, Igor F, Stocking, Emily, Kouznetsova, Valentina L, Price, Diana, Paulino, Amy, Gonzales, Tania, Overk, Cassia R, Patrick, Christina, Rockenstein, Edward, Masliah, Eliezer
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290715/
https://ncbi.nlm.nih.gov/pubmed/25117211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12875
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