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Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes

Arc is a unique immediate early gene whose expression is induced as synapses are being modified during learning. The uniqueness comes from the fact that newly synthesized Arc mRNA is rapidly transported throughout dendrites where it localizes near synapses that were recently activated. Here, we summ...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Steward, Oswald, Farris, Shannon, Pirbhoy, Patricia S., Darnell, Jennifer, Driesche, Sarah J. Van
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290588/
https://ncbi.nlm.nih.gov/pubmed/25628532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00101
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