Synaptically driven phosphorylation of ribosomal protein S6 is differentially regulated at active synapses versus dendrites and cell bodies by MAPK and PI3K/mTOR signaling pathways

High-frequency stimulation of the medial perforant path triggers robust phosphorylation of ribosomal protein S6 (rpS6) in activated dendritic domains and granule cell bodies. Here we dissect the signaling pathways responsible for synaptically driven rpS6 phosphorylation in the dentate gyrus using ph...

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Dades bibliogràfiques
Publicat a:Learn Mem
Autors principals: Pirbhoy, Patricia Salgado, Farris, Shannon, Steward, Oswald
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516686/
https://ncbi.nlm.nih.gov/pubmed/28716954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.044974.117
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