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Selective Localization of Arc mRNA in Dendrites Involves Activity- and Translation-Dependent mRNA Degradation

Arc is an immediate early gene that is unique among neuronal mRNAs because its transcripts are transported into dendrites and accumulate near activated synapses, presumably to be translated locally. These qualities pose Arc as playing an important, yet not fully understood, role in the activity-depe...

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Bibliografiske detaljer
Main Authors: Farris, Shannon, Lewandowski, Gail, Cox, Conor D., Steward, Oswald
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965778/
https://ncbi.nlm.nih.gov/pubmed/24671994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4944-13.2014
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