DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA.

We have incorporated the DNA-cleaving moiety o-phenanthroline-copper at amino acid 10 of the Msx-1 homeodomain, and we have analyzed site-specific DNA cleavage by the resulting Msx-1 derivative. We show that amino acid 10 of the Msx-1 homeodomain is close to the 5' end of the consensus DNA site...

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Detalhes bibliográficos
Main Authors: Shang, Z, Ebright, Y W, Iler, N, Pendergrast, P S, Echelard, Y, McMahon, A P, Ebright, R H, Abate, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42897/
https://ncbi.nlm.nih.gov/pubmed/7904065
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