Orientation of the Lac repressor DNA binding domain in complex with the left lac operator half site characterized by affinity cleaving.
Lac repressor (LacR) is a helix-turn-helix motif sequence-specific DNA binding protein. Based on proton NMR spectroscopic investigations, Kaptein and co-workers have proposed that the helix-turn-helix motif of LacR binds to DNA in an orientation opposite to that of the helix-turn-helix motifs of lam...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1991
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328881/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1923807/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.19.5233 |
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