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Orientation of the Lac repressor DNA binding domain in complex with the left lac operator half site characterized by affinity cleaving.

Lac repressor (LacR) is a helix-turn-helix motif sequence-specific DNA binding protein. Based on proton NMR spectroscopic investigations, Kaptein and co-workers have proposed that the helix-turn-helix motif of LacR binds to DNA in an orientation opposite to that of the helix-turn-helix motifs of lam...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Shin, J A, Ebright, R H, Dervan, P B
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1991
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328881/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1923807/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.19.5233
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