DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA.

We have incorporated the DNA-cleaving moiety o-phenanthroline-copper at amino acid 10 of the Msx-1 homeodomain, and we have analyzed site-specific DNA cleavage by the resulting Msx-1 derivative. We show that amino acid 10 of the Msx-1 homeodomain is close to the 5' end of the consensus DNA site 5'-(...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Shang, Z, Ebright, Y W, Iler, N, Pendergrast, P S, Echelard, Y, McMahon, A P, Ebright, R H, Abate, C
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1994
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7904065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.118
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