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DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA.

We have incorporated the DNA-cleaving moiety o-phenanthroline-copper at amino acid 10 of the Msx-1 homeodomain, and we have analyzed site-specific DNA cleavage by the resulting Msx-1 derivative. We show that amino acid 10 of the Msx-1 homeodomain is close to the 5' end of the consensus DNA site 5'-(...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Shang, Z, Ebright, Y W, Iler, N, Pendergrast, P S, Echelard, Y, McMahon, A P, Ebright, R H, Abate, C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1994
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42897/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7904065/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.118
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