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Antibiotics as Probes of Ribosome Structure: Binding of Chloramphenicol and Erythromycin to Polyribosomes; Effect of Other Antibiotics

Antibiotics were used as probes of ribosome topology and function. Studies of [(14)C]chloramphenicol and [(14)C]erythromycin binding to ribosomes and polyribosomes revealed the following features. The requirement of high K(+) concentration (150 mM) for [(14)C]chloramphenicol binding to NH(4)Cl-washe...

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Autore principale: Pestka, Sidney
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1974
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC428957/
https://ncbi.nlm.nih.gov/pubmed/4599122
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