DNA copy number evolution in Drosophila cell lines

BACKGROUND: Structural rearrangements of the genome resulting in genic imbalance due to copy number change are often deleterious at the organismal level, but are common in immortalized cell lines and tumors, where they may be an advantage to cells. In order to explore the biological consequences of...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Lee, Hangnoh, McManus, C Joel, Cho, Dong-Yeon, Eaton, Matthew, Renda, Fioranna, Somma, Maria Patrizia, Cherbas, Lucy, May, Gemma, Powell, Sara, Zhang, Dayu, Zhan, Lijun, Resch, Alissa, Andrews, Justen, Celniker, Susan E, Cherbas, Peter, Przytycka, Teresa M, Gatti, Maurizio, Oliver, Brian, Graveley, Brenton, MacAlpine, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289277/
https://ncbi.nlm.nih.gov/pubmed/25262759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-8-r70
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