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A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity

The protein phosphatase 2A (PP2A) is a conserved heterotrimeric enzyme that regulates several cellular processes including the DNA damage response and mitosis. Consistent with these functions, PP2A is mutated in many types of cancer and acts as a tumor suppressor. In mammalian cells, PP2A inhibition...

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Vydáno v:Genetics
Hlavní autoři: Merigliano, Chiara, Marzio, Antonio, Renda, Fioranna, Somma, Maria Patrizia, Gatti, Maurizio, Vernì, Fiammetta
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340330/
https://ncbi.nlm.nih.gov/pubmed/28040742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.192781
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