DNA copy number evolution in Drosophila cell lines

BACKGROUND: Structural rearrangements of the genome resulting in genic imbalance due to copy number change are often deleterious at the organismal level, but are common in immortalized cell lines and tumors, where they may be an advantage to cells. In order to explore the biological consequences of...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Lee, Hangnoh, McManus, C Joel, Cho, Dong-Yeon, Eaton, Matthew, Renda, Fioranna, Somma, Maria Patrizia, Cherbas, Lucy, May, Gemma, Powell, Sara, Zhang, Dayu, Zhan, Lijun, Resch, Alissa, Andrews, Justen, Celniker, Susan E, Cherbas, Peter, Przytycka, Teresa M, Gatti, Maurizio, Oliver, Brian, Graveley, Brenton, MacAlpine, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289277/
https://ncbi.nlm.nih.gov/pubmed/25262759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-8-r70
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