Competing RNA secondary structures are required for mutually exclusive splicing of the Dscam exon 6 cluster

Alternative splicing of eukaryotic pre-mRNAs is an important mechanism for generating proteome diversity and regulating gene expression. The Drosophila melanogaster Down Syndrome Cell Adhesion Molecule (Dscam) gene is an extreme example of mutually exclusive splicing. Dscam contains 95 alternatively...

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Bibliografiske detaljer
Main Authors: May, Gemma E., Olson, Sara, McManus, C. Joel, Graveley, Brenton R.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022272/
https://ncbi.nlm.nih.gov/pubmed/21159795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2521311
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