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Competing RNA secondary structures are required for mutually exclusive splicing of the Dscam exon 6 cluster

Alternative splicing of eukaryotic pre-mRNAs is an important mechanism for generating proteome diversity and regulating gene expression. The Drosophila melanogaster Down Syndrome Cell Adhesion Molecule (Dscam) gene is an extreme example of mutually exclusive splicing. Dscam contains 95 alternatively...

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Detalhes bibliográficos
Main Authors: May, Gemma E., Olson, Sara, McManus, C. Joel, Graveley, Brenton R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022272/
https://ncbi.nlm.nih.gov/pubmed/21159795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2521311
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