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Competing RNA secondary structures are required for mutually exclusive splicing of the Dscam exon 6 cluster

Alternative splicing of eukaryotic pre-mRNAs is an important mechanism for generating proteome diversity and regulating gene expression. The Drosophila melanogaster Down Syndrome Cell Adhesion Molecule (Dscam) gene is an extreme example of mutually exclusive splicing. Dscam contains 95 alternatively...

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Библиографические подробности
Главные авторы: May, Gemma E., Olson, Sara, McManus, C. Joel, Graveley, Brenton R.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022272/
https://ncbi.nlm.nih.gov/pubmed/21159795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2521311
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