SOLUBLE GUANYLATE CYCLASE IS REQUIRED FOR SYSTEMIC VASODILATION BUT NOT POSITIVE INOTROPY INDUCED BY NITROXYL (HNO) in the MOUSE

Nitroxyl (HNO), the reduced and protonated form of nitric oxide (NO(.)), confers unique physiological effects including vasorelaxation and enhanced cardiac contractility. These features have spawned current pharmaceutical development of HNO donors as heart failure therapeutics. HNO interacts with se...

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Pubblicato in:Hypertension
Autori principali: Zhu, Guangshuo, Groneberg, Dieter, Sikka, Gautam, Hori, Daijiro, Ranek, Mark J., Nakamura, Taishi, Takimoto, Eiki, Paolocci, Nazareno, Berkowitz, Dan E., Friebe, Andreas, Kass, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289094/
https://ncbi.nlm.nih.gov/pubmed/25452469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04285
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