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The Pharmacology of Nitroxyl (HNO) and Its Therapeutic Potential: Not Just the Janus Face of NO()

Nitroxyl (HNO), the one-electron reduced and protonated congener of nitric oxide (NO), has received recent attention as a potential pharmacological agent for the treatment of heart failure and as a pre-conditioning agent to mitigate ischemia-reperfusion injury, among other possible uses. The interes...

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Bibliographic Details
Main Authors: Paolocci, Nazareno, Jackson, Matthew I., Lopez, Brenda E., Tocchetti, Carlo G., Wink, David A., Hobbs, Adrian, Fukuto, Jon M.
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501193/
https://ncbi.nlm.nih.gov/pubmed/17222913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2006.11.002
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