PPARα via HNF4α regulates the expression of genes encoding hepatic amino acid catabolizing enzymes to maintain metabolic homeostasis

The liver is the main organ involved in the metabolism of amino acids (AA), which are oxidized by amino acid catabolizing enzymes (AACE). Peroxisome proliferator-activated receptor-α (PPARα) stimulates fatty acid β-oxidation, and there is evidence that it can modulate hepatic AA oxidation during the...

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Pubblicato in:Genes Nutr
Autori principali: Contreras, Alejandra V., Rangel-Escareño, Claudia, Torres, Nimbe, Alemán-Escondrillas, Gabriela, Ortiz, Victor, Noriega, Lilia G., Torre-Villalvazo, Ivan, Granados, Omar, Velázquez-Villegas, Laura A., Tobon-Cornejo, Sandra, González-Hirschfeld, Diana, Recillas-Targa, Félix, Tejero-Barrera, Elizabeth, Gonzalez, Frank J., Tovar, Armando R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288992/
https://ncbi.nlm.nih.gov/pubmed/25576393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-014-0452-0
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