PPARα via HNF4α regulates the expression of genes encoding hepatic amino acid catabolizing enzymes to maintain metabolic homeostasis

The liver is the main organ involved in the metabolism of amino acids (AA), which are oxidized by amino acid catabolizing enzymes (AACE). Peroxisome proliferator-activated receptor-α (PPARα) stimulates fatty acid β-oxidation, and there is evidence that it can modulate hepatic AA oxidation during the...

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Detalhes bibliográficos
Publicado no:Genes Nutr
Main Authors: Contreras, Alejandra V., Rangel-Escareño, Claudia, Torres, Nimbe, Alemán-Escondrillas, Gabriela, Ortiz, Victor, Noriega, Lilia G., Torre-Villalvazo, Ivan, Granados, Omar, Velázquez-Villegas, Laura A., Tobon-Cornejo, Sandra, González-Hirschfeld, Diana, Recillas-Targa, Félix, Tejero-Barrera, Elizabeth, Gonzalez, Frank J., Tovar, Armando R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288992/
https://ncbi.nlm.nih.gov/pubmed/25576393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-014-0452-0
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